Certified Reference Materials (CRMs)

Genetically modified crops have been commercially available since the mid-nineties. Due to opposing views on genetically modified crops, laws governing importation of these crops varies. AOCS provides Certified Reference Materials for labs to test for the presence of genetically modified traits.

 

The European Commission (EC) has mandated that as of 2004, a validated published method for detecting a new genetically modified event and a CRM must be available before the EC will authorize a new crop. Several nations outside of Europe require grain and ingredients to be labeled as genetically modified when trait levels exceed mandated thresholds. AOCS CRMs are used by labs that perform those analyses.


This program is A2LA accredited to ISO Guide 17034:2016. These CRMs are intended for use as quality control materials or calibrants in methods for the detection, identification, and/or quantification of genetically modified events.

CRM order, shipping, and tariff information (.pdf)

AOCS Scope of Accreditation (.pdf)

Reference list of currently available CRMs (.pdf)


AOCS 0208-A5 was prepared from canola genomic DNA extracted from clean T45 canola leaves provided by Bayer CropScience NV. T45 was prepared by introducing the pat (syn) gene to confer glufosinate herbicide tolerance. 

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AOCS 0304-A2 was prepared from non-modified canola seed (variety 'Eagle') provided by Monsanto Company.

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AOCS 0304-B2 was prepared from canola seed (GT73/RT73) provided by Monsanto Company. GT73/RT73 was prepared by introducing the cp4 epsps (aroA:CP4) and goxv247 genes to confer glyphosphate herbicide tolerance. 

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AOCS 0306-B4 was prepared from canola genomic DNA extracted from clean non-modified canola leaves provided by Bayer CropScience NV.

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AOCS 0306-F6 was prepared from canola genomic DNA extracted from clean Ms8 canola leaves provided by Bayer CropScience NV. Ms8 was prepared by introducing the bar and barnase genes to confer glufosinate herbicide tolerance and male sterility. 

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AOCS 0306-G5 was prepared from canola genomic DNA extracted from clean Rf3 canola leaves provided by Bayer CropScience NV. Rf3 was prepared by introducing the bar and barstar genes to confer glufosinate herbicide tolerance and fertility restoration. 

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AOCS 0711-A2 was prepared from canola genomic DNA extracted from clean Ms1 canola leaves provided by Bayer CropScience NV. Ms1 was prepared by introducing the bar, barnase, and nptⅡ genes to confer glufosinate herbicide tolerance, male sterility, and antibiotic resistance.

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AOCS 0711-B2 was prepared from canola genomic DNA extracted from clean Rf1 canola leaves provided by Bayer CropScience NV. Rf1 was prepared by introducing the bar, barstar, and nptⅡ genes to confer glufosinate herbicide tolerance, fertility restoration, and antibiotic resistance. 

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AOCS 0711-C2 was prepared from canola genomic DNA extracted from clean Rf2 canola leaves provided by Bayer CropScience NV. Rf2 was prepared by introducing the bar, barstar, and nptⅡ genes to confer glufosinate herbicide tolerance, fertility restoration, and antibiotic resistance. 

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AOCS 0711-D3 was prepared from canola genomic DNA extracted from clean Topas 19/2 canola leaves provided by Bayer CropScience NV. Topas 19/2 was prepared by introducing the bar and nptⅡ genes to confer glufosinate herbicide tolerance and antibiotic resistance. 

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AOCS 1011-A was prepared from MON88302 canola seed provided by Monsanto Company. MON88302 was prepared by introducing the cp4 epsps (aroA:CP4) gene to confer glyphosphate herbicide tolerance. 

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AOCS 0113-A was prepared from MON88701 cottonseed provided by Monsanto Company. MON88701 was prepared by introducing the dmo and bar genes to confer glufosinate and dicamba herbicide tolerance. 

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AOCS 0306-A3 was prepared from cotton genomic DNA extracted from clean non-modified cotton leaves provided by Bayer CropScience NV.

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AOCS 0306-E2 was prepared from cotton genomic DNA extracted from clean LLCotton25 cotton leaves provided by Bayer CropScience NV. LLCotton25 was prepared by introducing the bar gene to confer glufosinate herbicide tolerance. 

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AOCS 0804-A was prepared from non-modified cottonseed provided by Monsanto Company.

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AOCS 0804-B was prepared from MON1445 cottonseed provided by Monsanto Company. MON1445 was prepared by introducing the cp4 epsps (aroA:CP4), nptⅡ, and aad genes to confer glyphosphate herbicide tolerance and antibiotic resistance. 

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AOCS 0804-C was prepared from MON531 cottonseed provided by Monsanto Company. MON531 was prepared by introducing the cry1Ac, nptⅡ, and aad genes to confer lepidopteran insect resistance and antibiotic resistance. 

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AOCS 0804-D was prepared from MON15985-7 cottonseed provided by Monsanto Company. MON15985-7 was prepared by introducing the cry1Ac, nptⅡ, aad, uidA, and cry2Ab2 genes to confer lepidoteran insect resistance, antibiotic resistance, and visual marker.

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AOCS 0906-D was prepared from MON88913 cottonseed provided by Monsanto Company. MON88913 was prepared by introducing the cp4 epsps (aroA:CP4) gene to confer glyphosphate herbicide tolerance. 

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AOCS 1012-A was prepared from non-modified cotton provided by Syngenta Crop Protection, LLC.

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AOCS 1012-C was prepared from COT102 cotton provided by Syngenta Crop Protection, LLC. COT102 was prepared by introducing the vip3A(a) and aph4 (hpt) genes to confer lepidopteran insect resistance and antibiotic resistance. 

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AOCS 1108-A5 was prepared from cotton genomic DNA extracted from clean GHB614 cotton leaves provided by Bayer CropScience NV. GHB614 was prepared by introducing the 2mepsps gene to confer glyphosphate herbicide tolerance. 

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AOCS 0306-C2 was prepared from maize genomic DNA extracted from clean non-modified maize leaves provided by Bayer CropScience NV.

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AOCS 0306-H9 was prepared from maize genomic DNA extracted from clean T25 maize leaves provided by Bayer CropScience NV. T25 was prepared by introducing the pat (syn) and bla genes to confer glufosinate herbicide tolerance and antibiotic resistance. 

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AOCS 0406-A was prepared from non-modified maize provided by Monsanto Company.

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AOCS 0406-D was prepared from MON88017 maize provided by Monsanto Company. MON88017 was prepared by introducing the cp4 epsps (aroA:CP4) and cry3Bb1 genes to confer glyphosphate herbicide tolerance and coleopteran insect resistance. 

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AOCS 0407-A was prepared from non-modified maize provided by Syngenta Biotechnology Inc.

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AOCS 0407-B was prepared from GA21 maize provided by Syngenta Biotechnology Inc. GA21 was prepared by introducing the mepsps gene to confer glyphosphate herbicide tolerance. 

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AOCS 0411-C was prepared from non-modified maize, and is sold as a kit with AOCS 0411-D, which was prepared from 5307 maize. These CRMs were provided by Syngenta Biotechnology Inc. 5307 was prepared by introducing the pmi and ecry3.1Ab genes to confer multiple insect resistance and mannose metabolism. 

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AOCS 0512-A was prepared from MON87427 maize provided by Monsanto Company. MON87427 was prepared by introducing the cp4 epsps (aroA:CP4) gene to confer glyphosphate herbicide tolerance. 

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AOCS 0607-A2 was prepared from MIR604 maize provided by Syngenta Biotechnology Inc. MIR604 was prepared by introducing the mcry3A and pmi genes to confer coleopteran insect resistance and mannose metabolism. 

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AOCS 0709-A was prepared from MON87460 maize provided by Monsanto Company. MON87460 was prepared by introducing the cspB and nptⅡ genes to confer drought stress tolerance and antibiotic resistance. 

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AOCS 0906-E was prepared from MON89034 maize provided by Monsanto Company. MON89034 was prepared by introducing the cry2Ab2 and cry1A.105 genes to confer lepidopteran insect resistance. 

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AOCS 1208-A was prepared from MIR162 maize provided by Syngenta Biotechnology Inc. MIR162 was prepared by introducing the vip3Aa20 and pmi genes to confer lepidopteran insect resistance and mannose metabolism. 

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AOCS 0806-A was prepared from non-modified potato provided by BASF Plant Science.

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AOCS 0806-B was prepared from non-modified potato provided by BASF Plant Science.

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AOCS 0306-D4 was prepared from rice genomic DNA extracted from clean non-modified rice leaves provided by Bayer CropScience NV.

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AOCS 0306-I8 was prepared from rice genomic DNA extracted from clean LLRice62 rice leaves provided by Bayer CropScience NV. LLRice62 was prepared by introducing the bar gene to confer glufosinate herbicide resistance. 

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AOCS 0210-A was prepared from MON87705 soybeans provided by Monsanto Company. MON87705 was prepared by introducing the fatb1-A, fad2-1A, and cp4 epsps (aroA:CP4) genes to confer modified oil/fatty acid and glyphosphate herbicide tolerance. 

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AOCS 0311-A was prepared from MON87708 soybeans provided by Monsanto Company. MON87708 was prepared by introducing the dmo and cp4 epsps (aroA:CP4) genes to confer dicamba and glyphosphate herbicide tolerance. 

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AOCS 0610-A3 was prepared from soybean genomic DNA extracted from clean FG72 soybean leaves provided by Bayer CropScience NV. FG72 was prepared by introducing the 2mepsps and hppdPF W336 genes to confer glyphosphate and isoxaflutole herbicide tolerance. 

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AOCS 0707-A7 was prepared from soybean genomic DNA extracted from clean non-modified soybean leaves provided by Bayer CropScience NV.

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AOCS 0707-B9 was prepared from soybean genomic DNA extracted from clean A2704-12 soybean leaves provided by Bayer CropScience NV. A2704-12 was prepared by introducing the pat gene to confer glufosinate herbicide resistance. 

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AOCS 0707-C6 was prepared from soybean genomic DNA extracted from clean A5547-127 soybean leaves provided by Bayer CropScience NV. A5547-127 was prepared by introduing the pat gene to confer glufosinate herbicide resistance. 

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AOCS 0809-A was prepared from MON87701 soybeans provided by Monsanto Company. MON87701 was prepared by introducing the cry1Ac gene to confer lepidopteran insect resistance. 

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AOCS 0809-B was prepared from MON87769 soybeans provided by Monsanto Company. MON87769 was prepared by introducing the Pj.D6D, Nc.Fad3, and cp4 epsps (aroA:CP4) genes to confer modified oil/fatty acid and glyphosphate herbicide tolerance. 

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AOCS 0906-A was prepared from non-modified soybeans provided by Monsanto Company.

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AOCS 0906-B was prepared from MON89788 soybeans provided by Monsanto Company. MON89788 was prepared by introducing the cp4 epsps (aroA:CP4) gene to confer glyphosphate herbicide tolerance. 

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AOCS 0911-A was prepared from non-modified soybeans provided by BASF Plant Science.

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AOCS 0911-B was prepared from non-modified soybeans provided by BASF Plant Science.

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AOCS 0911-C was prepared from BPS-CV127-9 soybeans provided by BASF Plant Science. BPS-CV127-9 was prepared by introducing the csr1-2 gene to confer sulfonylurea herbicide tolerance. 

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AOCS 0911-D was prepared from BPS-CV127-9 soybeans provided by BASF Plant Science. BPS-CV127-9 was prepared by introducing the csr1-2 gene to confer sulfonylurea herbicide tolerance. 

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AOCS 1206-A was prepared from non-modified sugar beet seed provided by Monsanto Company.

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AOCS 1206-B was prepared from H7-1 sugar beet seed provided by Monsanto Company. H7-1 was prepared by introducing the cp4 epsps (aroA:CP4) gene to confer glyphosate herbicide tolerance.

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